Table V.

Cascade Impaction Results of Lyophilized Paclitaxel Nanoparticle Agglomerates (Values=Average±S.D.)

Characteristics of the lyophilized NAd			Formulations
			F1a	F2b	F1 Combc	Paclitaxel as received	Cisplatin as received
At flow rate of ~30 L/min	% EFe		72±5	72±15	78±1	68±6	70±1
	% FPFf	<5.7	96±3	95±4	79±1	0.4±0.3	0.3±0.4
		<3.3	84±3	80±5	71±1	0	0
	MMADg		1.5±0.1	1.9±0.4	1.8±0.04	9.5±0.04	9.5±0.1
	GSDh		2.2±0.1	2.3±0.1	2.2±0.2	1.9±0.1	3.5±0.1

^aF1=0.1:0.02:0.01; Px:Lec:PVP K90

^bF2=0.1:0.02; Px:Lec

^cF1 Comb=3:2; PX:CP

^dNA: nanoparticle agglomerates

^e% EF: percent emitted fraction

^fFPF: fine particle fraction

^gMMAD: mass median aerodynamic diameter obtained from cascade impactor

^hGSD: geometric standard deviation