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. Author manuscript; available in PMC: 2014 Aug 6.
Published in final edited form as: Pharm Res. 2009 May 5;26(7):1752–1763. doi: 10.1007/s11095-009-9886-2

Table VII.

Yield, Loading and Dissolution Behavior of Paclitaxel Nanoparticle Agglomerates (Values=Average±S.D.)

Characteristics Formulations
F1a F2b F1 Combc
Process yield of lyophilized NAd 86±3% 90±3% 89±2%
% Drug loading of PX and CP in the lyophilized NAd 85±4% 86±9% 93±4% (PX)
90±5% (CP)
Q8hf NPe 66±2% 61±13% n/a
Q8hf NAd 44±4% 40±3% 61±5% (PX)
100±2% (CP)
a

F1=0.1:0.02:0.01; PX:Lec:PVP K90

b

F2=0.1:0.02; PX:Lec

c

F1 Comb=3:2; PX:CP

d

NA: nanoparticle agglomerates

e

NP: nanoparticles

f

Q8h: % Paclitaxel (PX) and cisplatin (CP) dissolved after 8 h