Figure 5.
Schematic illustrating magnetically induced hyperthermia and drug release. (A) Magnetic nanoparticles (NPs) at a defined concentration, when exposed to an alternating magnetic field, can induce a temperature rise as a consequence of their magnetic vibrations. (B) Heat produced locally by the magnetic NP can be used to release drugs associated to the NP surface via thermosensitive linkers.91−93 In this case, drug release could occur even if the global temperature of the system does not change macroscopically; a local temperature increase is responsible for such release.91,92,94