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. Author manuscript; available in PMC: 2014 Aug 6.
Published in final edited form as: Proteomics. 2013 Jan;13(1):48–60. doi: 10.1002/pmic.201200188

Figure 4.

Figure 4

STRING diagrams. (A) Cell cycle proteins identified in all MCF-7 fractions: (1) cell cycle regulation; (2) proteasome degradation; (3) chromatin maintenance; (4) DNA repair; (5) mitosis/cytokinesis; (6) nuclear import/export; (7) integrin signaling; (8) G1 arrest proteins; (9) ribosome biogenesis. (B) Up-regulated proteins in G1N: (1) DNA damage repair/transcription repression; (2) transcription activation/repression; (3) transcription initiation (Mediator proteins); (4) transcription activation/cell motily/adhesion; (5) nuclear lamina organization; (6) ribosome biogenesis/translation initiation; (7) translation/amino acid metabolism; (C) Up-regulated proteins in SN: (1) cell proliferation/cell cycle regulation; (2) transcription/rRNA processing, (3) mitochondrial protein metabolism; (4) mitochondrial metabolism; (5) protein folding.