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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Virology. 2014 Mar 14;0:237–246. doi: 10.1016/j.virol.2014.01.027

Figure 6. Monoclonal antibodies targeting the receptor binding surface inhibit fusion between cells infected with MV-Hedm but not Retargeted MVs.

Figure 6

Vero-His cells were infected with control MV-Hedm (i) or retargeted MV derivatives (ii–vii) for 13 hours prior to replacing the media with media containing mAbs targeting the receptor binding surface. Average syncytia size was quantified by counting the number of nuclei per syncytium and allocating a score (viii) of +/− (≤ 5 nuclei/cells per syncytium), + (6–20 nuclei/cells per syncytium), ++ (21–50 nuclei/cells per syncytium), or +++ (>50 nuclei/cells per syncytium) (table viii). The data is presented as the % of syncytia of the indicated size per 20 syncytia per well. * astrix marks percentage of syncytia that have > 50 nuclei/cells per syncytium in the presence of mAbs BH97, 20H6, I-41