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. Author manuscript; available in PMC: 2015 Jul 15.
Published in final edited form as: Cancer Res. 2014 May 8;74(14):3716–3726. doi: 10.1158/0008-5472.CAN-13-3116

Figure 3. MB cell invasiveness is mediated by neogenin and UNC5B.

Figure 3

A,B, The netrin-1 receptor protein (A) and mRNA (B) expression levels were analyzed by western blot and qRT-PCR, respectively. N.D. stands for “not detected.” C,D, D458 cells were transfected with control, UNC5B or neogenin siRNA. Receptor expression was measured by western blot, and MB cell invasiveness was assessed in Matrigel-coated Transwells. E,F, D458 cells were transfected with control, neogenin or netrin-1 siRNA. Receptor expression was measured by western blot, and MB cell invasiveness was assessed in Matrigel-coated Transwells. Data represent the mean ± SD (n=3), * p < 0.05.