Table 1.
Gene Name | Gene Symbol | Parametric P-value | Fold Change in K303R Clones |
---|---|---|---|
Leptin receptor | ObR/LepR | <1e-07 | 2.4 |
Interleukin 28 receptor α | IL28RA | <1e-07 | 1.9 |
Chemokine (C-X-C motif) receptor 4 | CXCR4 | <1e-07 | 1.9 |
Insulin receptor | IR | 1.7e-06 | 1.68 |
Interleukin 17 receptor C | IL17RC | 7e-07 | 1.6 |
Insulin-like growth factor 2 receptor | IGF2R | 1e-07 | 1.57 |
Interleukin 15 receptor β | IL15RA | 3e-07 | 1.5 |
Macrophage stimulating receptor 1 | MSR1 | 9.2e-06 | 1.44 |
Hepatocyte growth factor receptor | MET | 1.69e-05 | 1.39 |
Interleukin 1 receptor, type I | IL1R1 | 0.0004 | 1.38 |
Chemokine (C-C motif) receptor 7 | CCR7 | 0.0001 | 1.3 |
Chemokine (C-X3-C motif) | CX3CR1 | 7.9e-05 | 1.32 |
receptor 1 | 1.27 | ||
Interleukin 2 receptor β | IL2RB | 3.57e-05 | 1.25 |
Interleukin 9 receptor | IL9R | 0.0002 | 1.23 |
Interleukin 10 receptor β | IL10RB | 0.0003 | 1.21 |
Interleukin 6 receptor | IL6R | 0.01 | 1.2 |
Interleukin 21 receptor | IL21R | 0.0006 | 0.8 |
Interleukin 4 receptor | IL4R | 0.0007 | 0.7 |
Epidermal growth factor receptor | EGFR | 7.6e-06 | 0.7 |
Insulin-like growth factor 1 receptor | IGF1R | 0.0006 | 0.7 |
Fibroblast growth factor receptor 3 | FGFR3 | 0.0005 | 0.7 |
Representative probesets from pathway analysis showing gene expression changes in the receptor family of CAFs-secreted factors along with the p-value and the fold change of K303R-expressing cells compared to WT cells studied by microarray analysis. In cases where the same genes were deemed significant across multiple probesets, only one is shown.