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. Author manuscript; available in PMC: 2015 Jan 15.
Published in final edited form as: Cell Host Microbe. 2014 Jan 15;15(1):1–2. doi: 10.1016/j.chom.2013.12.005

Figure 1. Mycobacterial Cell Wall Lipids Modulate Macrophage Composition at the Earliest Sites of Infection.

Figure 1

PDIM suppresses the recruitment of microbicidal, iNOS-positive macrophages by inhibiting TLR signaling, while PGL stimulates the recruitment of more permissive, iNOS-negative macrophages via the CCR2 pathway.