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Mean (Standard Deviation) Pharmacokinetic Parameters
| Tedizolid Phosphate11 (200 mg PO once daily) | Linezolid6 (600 mg PO twice daily) | |
|---|---|---|
| Cmax (mg/L) | 2.2 ± 0.6 | 21.2 ± 5.78 |
| Tmax (hours) | 3.5 (1.0 to 6.0) † | 1.03 ± 0.62 |
| T½ (hours) | 12 | 5.4 ± 2.06 |
| Clearance (L/hr) | 8.4 ± 2.1 | 4.8 ± 1.74 |
| AUC (mcg*hr/mL) | 25.6 ± 8.4 | 138 ± 42.1 |
Median (range)
