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. Author manuscript; available in PMC: 2015 Apr 15.
Published in final edited form as: J Immunol. 2014 Mar 17;192(8):3816–3827. doi: 10.4049/jimmunol.1301738

Figure 4. Translocation of monocytes during light-induced retinal degeneration.

Figure 4

A. Flat-mount RPE was examined 7 days after light exposure at 10,000 lux for 30 min under a fluorescent microscope with 4-week-old Cx3Cr1gfp/Δ Abca4-/-Rdh8-/- and Abca4-/-Rdh8-/- mice. Bars indicate 25 μm. B. Shapes of GFP-positive cells were examined in 4-week-old Cx3Cr1gfp/ΔAbca4-/-Rdh8-/- mice by flat-mount eyes 7 days after exposure to light at 10,000 lux for 30 min at different depth of the retina. GFP signals are shown in green in the left and right panels and autofluorescent signals are shown in red. Bars indicate 25 μm. C. GFP-positive cells at the ONL~RPE level is presented. Cx3Cr1gfp/ΔAbca4-/-Rdh8-/- mice were exposure to light at 10,000 lux for 30 min and flat-mount retina was prepared 7 days after light. Bar indicates 100 μm. D. SLO images were captured from 4-week-old Cx3Cr1gfp/ΔAbca4-/-Rdh8-/- mice before and 7 days after light exposure at 10,000 lux for 30 min Bars indicate 100 μm.