Table 3.
Outcomes |
Number of studies |
Sample size |
Heterogeneity (
P, I
2
) |
Overall effect size |
95% CI of overall effect |
P
|
|
---|---|---|---|---|---|---|---|
LAP | OPEN | ||||||
Operation time (min) |
8 |
203 |
233 |
<0.001, 82% |
WMD = 12.03 |
-8.03, 32.09 |
0.24 |
Blood loss (ml) |
5 |
118 |
151 |
0.03, 64% |
WMD = -48.29 |
-78.23, -18.36 |
<0.01 |
Time to first flatus (d) |
6 |
119 |
144 |
0.10, 46% |
WMD = -1.35 |
-1.66, -1.03 |
<0.01 |
Time to oral intake (d) |
7 |
182 |
208 |
0.001, 73% |
WMD = -1.67 |
-2.19, -1.15 |
<0.01 |
Hospital stay (d) |
8 |
203 |
233 |
0.002, 68% |
WMD = -2.53 |
-3.50, -1.57 |
<0.01 |
Overall complications |
8 |
203 |
233 |
0.70, 0% |
RR = 0.47 |
0.22, 1.01 |
0.05 |
Tumor size (cm) |
8 |
203 |
233 |
0.10, 42% |
WMD = -0.77 |
-1.23, -0.31 |
<0.01 |
Recurrence | 5 | 130 | 165 | 0.95, 0% | RR = 1.01 | 0.39, 2.63 | 0.99 |
CI, confidence interval; LAP, laparoscopic surgery; OPEN, open surgery; RR, risk ratio; WMD, weighted mean difference.