Figure 2.
Four genomic loci analyzed by HyCCAPP. The four DNA regions studied are depicted by the pink ovals. These include the 25S and 5S regions of the rDNA locus (a 150 copy 9 kb tandem repeat on chromosome XII), the X-element (a 35 copy 462 bp sequence near the telomeric repeats), and the single copy GAL1-10 promoter region. The 25S rDNA locus is transcribed as part of the 35S rRNA by RNA polymerase I, while the 5S rDNA locus is transcribed by RNA polymerase III. The X-element is located either directly adjacent to the telomeric repeats or separated by one or more copies of the Y′ element. The GAL1-10 promoter is a 660 bp region containing the upstream activating sequence (UAS) for divergent control of both the GAL1 and GAL10 genes.