Figure 4. Low estrogen levels decreased insulin expression in the hippocampus.
Insulin content in the serum (A) and CSF (B). (C) Insulin mRNA expression in the hippocampus was measured by quantitative RT-PCR. (D) Evaluation of insulin content in the hippocampus using ELISA. aP<0.05 and aaP<0.01, OVX group vs normal group. bP<0.05 and bbP<0.01, N+TAM group vs. normal group. cP<0.01, N+TAM group vs. OVX group. n = 8.