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. 2014 Aug 6;9(8):e104492. doi: 10.1371/journal.pone.0104492

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© 2014 Goodchild et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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K_SV for 6 µM monomer equivalent concentration β₂m monomer, fragmented or unfragmented fibrils 10 min after addition of LUVs (5 µM lipid) at 37°C in (A) Assay buffer at pH 7.4 or (B) Assay buffer at pH 4.5. Lipid mixes comprise 36 POPC: 20 POPE: 7 SM: 25 cholesterol (mol/mol) doped with 0 mol % (blue), 12 mol % (red) or 50 mol % (green) BMP. Error bars represent 1 S.E. from linear regression.