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. 2014 Aug 6;9(8):e104653. doi: 10.1371/journal.pone.0104653

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© 2014 Kotzerke et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Dose-dependent decrease in supercoiled DNA exposed to ^99mTc-pertechnetate or ^99mTc-HYNIC-DAPI for 2 (A) or 24 hours (B). The dose-dependent increase in open circular DNA was similar for both radiotracers, but the fraction of linear DNA was greater in the presence of ^99mTc-HYNIC-DAPI compared with ^99mTc-pertechnetate.