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. Author manuscript; available in PMC: 2014 Sep 1.

Published in final edited form as: Gene Ther. 2014 Jan 23;21(3):253–261. doi: 10.1038/gt.2013.79

a) Relationship between level of intact genomic Dnaic1 and MCC. Most animals with >20% Dnaic1 remaining had MCC rates > 2 mm/min and no evidence of disease. b) Histology of the nasal cavity of animals with 16% (left) and 19% (right) of the wild-type level of Dnaic1 showing the absence (left) or presence (right; arrow) of rhinosinusitis. The maxillary sinus (*) and nasal septum (arrow) are indicated (left). Sections were stained with alcian blue-periodic acid Schiff.

a) Relationship between level of intact genomic Dnaic1 and MCC. Most animals with >20% Dnaic1 remaining had MCC rates > 2 mm/min and no evidence of disease. b) Histology of the nasal cavity of animals with 16% (left) and 19% (right) of the wild-type level of Dnaic1 showing the absence (left) or presence (right; arrow) of rhinosinusitis. The maxillary sinus (*) and nasal septum (arrow) are indicated (left). Sections were stained with alcian blue-periodic acid Schiff.