Table 4.
The association between the BUD13/ZNF259 polymorphisms with hypertriglyceridaemia
| Hypertriglyceridaemia | ||||||
|---|---|---|---|---|---|---|
| SNP | Genotype | Genotype distribution, n (%) | OR (95% CI) | P-value | ||
| Cases (n = 254) | Controls (n = 850) | P-value | ||||
| ZNF259 1093-336G>A rs2075290 | AA | 103 (40.6) | 461 (54.2) | 1.17 (0.77, 1.76) | 0.466 | |
| AG/GG | 151 (59.4) | 389 (45.8) | 0.000 | |||
| MAF | 181 (35.2) | 440 (25.9) | 0.000 | |||
| ZNF259 *365 + 359C>G rs964184 | CC | 122 (48.0) | 522 (61.4) | 0.78 (0.42, 1.46) | 0.437 | |
| CG/GG | 132 (52.0) | 328 (38.6) | 0.000 | |||
| MAF | 156 (30.8) | 368 (21.7) | 0.000 | |||
| BUD13 237 + 1741T>C rs10790162 | GG | 118 (46.5) | 529 (62.2) | 1.38 (0.73, 2.6) | 0.322 | |
| GA/AA | 136 (53.5) | 321 (37.8) | 0.000 | |||
| MAF | 165 (32.5) | 363 (21.4)) | 0.000 | |||
| BUD13 323-575A>G rs17119975 | AA | 174 (68.5) | 546 (64.2) | 0.78 (0.60, 1.02) | 0.064 | |
| AG/GG | 80 (31.5) | 304 (35.8) | 0.210 | |||
| MAF | 85 (16.7) | 340 (20.0) | 0.101 | |||
| BUD13 *147C>T rs11556024 | CC | 220 (86.6) | 718 (84.5) | 0.85 (0.61, 1.19) | 0.339 | |
| CT/TT | 34 (13.4) | 132 (15.5) | 0.402 | |||
| MAF | 68 (13.4) | 135 (7.9) | 0.000 | |||
| BUD13 64G>T rs35585096 | CC | 251 (98.8) | 838 (98.6) | 1.37 (0.48, 3.91) | 0.551 | |
| CA | 3 (1.2) | 12 (1.4) | 0.781 | |||
| MAF | 6 (1.2) | 24 (1.4) | 0.861 | |||