Table S5.
Artificial tears with combinations of active ingredients
| Name | Active ingredients | Preservatives |
|---|---|---|
| Refresh Optive® Advanced | 0.5% CMC | Preserved-forma |
| 1.0% glycerine | Purite® (stabilized oxychloro complex) | |
| Refresh Optive® | 0.5% polysorbate 80 0.5% CMC |
Preserved-forma |
| Refresh Optive® Sensitive | 0.9% glycerine 0.5% CMC |
Purite® (stabilized oxychloro complex) None |
| Tears Naturale® II | 0.9% glycerine 0.3% HPMC |
Polyquad® (polyquaternium-1) |
| Tears Naturale® Free | 0.1% dextran 70 0.3% HPMC |
None |
| Tears Naturale® Forte | 0.1% dextran 70 0.3% HPMC 0.1% dextran 70 |
Polyquad® (polyquaternium-1) |
| Tears Naturale® – Bion Tears | 0.2% glycerin 0.3% HPMC 0.1% dextran 70 Zinc + bicarbonate |
None |
| Tears Renewed® | 0.3% HPMC | BAK |
| Hypotears® | 0.1% dextran 70 1.0% PVA |
BAK |
| Soothe® XP | 1.0% polyethylene glycol 1% light mineral oil 4.5% mineral oil |
Polyhexamethylene biguanide |
| Hylo®-Fresh | 0.03% hyaluronic acid | None |
| Hylo-Comod® | 0.1% hyaluronic acid | None |
| Similasan® Dry Eye Relief | Belladonna euphrasia Mercurius sublimatus |
Silver sulfate |
| Similasan® Irritated Eye Relief | Belladonna euphrasia Hepar sulfuris |
Silver sulfate |
Notes:
Both preserved and preservative-free formulations commercially available. Manufacturers are as follows: Refresh®, Allergan, Irvine, CA, USA; Tears Naturale®, Alcon Laboratories, Inc., Fort Worth, TX, USA; Tears Renewed®, Akorn, Incorporated, Lake Forest, IL, USA; Hypotears®, Novartis Pharmaceuticals, East Hanover, NJ, USA; Soothe®, Bausch & Lomb Incorporated, Bridgewater, NJ, USA; Hylo®-Fresh and Hylo-Comod®, URSAPHARM, Saarbrücken, Germany; Similasan®, Similasan Corporation, Highlands Ranch, CO, USA; Polyquad®, Alcon Laboratories, Inc.; Purite®, Bio-Cide International Inc., Norman, OK, USA.
Abbreviations: BAK, benzalkonium chloride; CMC, carboxy methylcellulose; HPMC, hydroxypropyl methylcellulose; PVA, polyvinyl alcohol.