Table 3.
Mean QOLRAD scores with 95% confidence intervals for patients with non-erosive reflux disease or reflux esophagitis and daily vs. no regurgitation at baseline and at week 4.
| QOLRAD dimension | GORD group | Mean (95% CI) | |||
|---|---|---|---|---|---|
| Patients with frequent and intense heartburn and daily regurgitation at baseline (NERD, n = 388*; RO, n = 382) | Patients with frequent and intense heartburn and no regurgitation at baseline (NERD, n = 108; RO, n = 113) | Patients with no or greatly improved heartburn at week 4 and daily regurgitation (NERD, n = 78; RO, n = 60) | Patients with no or greatly improved heartburn at week 4 and no regurgitation (NERD, n = 324; RO, n = 264) | ||
| Emotional distress | NERD | 3.47 (3.33 to 3.62) | 4.95 (4.67 to 5.23) | 6.13 (5.86 to 6.40) | 6.87 (6.82 to 6.92) |
| RO | 3.52 (3.38 to 3.67) | 4.88 (4.62 to 5.14) | 6.38 (6.13 to 6.63) | 6.88 (6.83 to 6.93) | |
| Food/drink problems | NERD | 3.09 (2.97 to 3.21) | 4.55 (4.31 to 4.80) | 5.87 (5.59 to 6.14) | 6.80 (6.74 to 6.86) |
| RO | 3.10 (2.98 to 3.22) | 4.23 (3.98 to 4.47) | 6.13 (5.85 to 6.41) | 6.84 (6.79 to 6.90) | |
| Sleep disturbance | NERD | 3.59 (3.44 to 3.75) | 5.10 (4.82 to 5.37) | 6.32 (6.10 to 6.55) | 6.90 (6.85 to 6.94) |
| RO | 3.30 (3.15 to 3.46) | 4.78 (4.48 to 5.08) | 6.27 (5.97 to 6.58) | 6.90 (6.85 to 6.95) | |
| Physical/social functioning | NERD | 4.46 (4.31 to 4.61) | 5.85 (5.64 to 6.06) | 6.45 (6.27 to 6.64) | 6.92 (6.88 to 6.97) |
| RO | 4.55 (4.40 to 4.70) | 5.84 (5.62 to 6.06) | 6.49 (6.24 to 6.75) | 6.94 (6.91 to 6.97) | |
| Vitality | NERD | 3.32 (3.19 to 3.46) | 4.81 (4.53 to 5.09) | 6.06 (5.81 to 6.31) | 6.83 (6.77 to 6.88) |
| RO | 3.40 (3.26 to 3.54) | 4.61 (4.32 to 4.90) | 6.20 (5.89 to 6.51) | 6.88 (6.82 to 6.93) | |
*
Physical/social functioning n = 387.
GORD, gastro-oesophageal reflux disease; NERD, non-erosive reflux disease; RO, reflux oesophagitis