Table 2. Univariate and multivariate logistic regression analysis of risk factors for DR.
Variate | Univariate logistic regression analysis |
Variate in the equation | Multivariate logistic forward regression analysis |
||||
---|---|---|---|---|---|---|---|
OR | 95%CI | P | OR | 95%CI | P | ||
Age |
0.87 |
0.76–0.98 |
0.023* |
Age |
0.80 |
0.66–0.97 |
0.023* |
IL-2 |
0.45 |
0.21–0.96 |
0.038* |
IL-2 |
0.59 |
0.22–1.54 |
0.281 |
IL-3 |
3.25 |
1.05–10.06 |
0.041* |
IL-3 |
2.01 |
0.39–10.50 |
0.406 |
TNF- α |
1.30 |
1.01–1.67 |
0.039* |
TNF- α |
1.40 |
0.93–2.10 |
0.106 |
TNF-β | 0.08 | 0.01–0.62 | 0.016* | TNF-β | 0.09 | 0.01–1.30 | 0.077 |
OR=odds ratios, CI=confidence intervals. *P value was significant (p<0.05) We subdivided the diabetic group into two groups: NDR (n=19) and DR (n=40). Univariate analysis screened age, IL-2, IL-3, TNF-α, and TNF-β as related factors to DR; OR values were 0.87 (p=0.023), 0.45 (p=0.038), 3.25 (p=0.041), 1.30 (p=0.039), and 0.08 (p=0.016), respectively. After that, multivariate logistic forward regression analysis excluded other factors except age (OR=0.80,p=0.023).