The Consortia of the Rare Diseases Clinical Research Network. *National Institutes of Health (NIH), Office of Rare Diseases Research/National Center for Advancing Translational Sciences (ORDR/NCATS), National Institute of Allergy and Infectious Diseases (NIAID), National Institute of Dental and Craniofacial Research (NIDCR), National Cancer Institute (NCI), National Institute of Neurological Disorders and Stroke (NINDS), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institute of Child Health and Human Development (NICHD), National Heart, Lung and Blood Institute (NHLBI), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Observational Study Monitoring Board/Data and Safety Monitoring Board (OSMB/DSMB).