Table 2.
Change in primary and secondary outcomes from baseline at 1 year, with mean difference and confidence interval data reported for log-transformed variables (n=17)
| Outcome variable | Baseline mean (SD) | One year mean (SD) | Mean difference | 95% CI
|
|
|---|---|---|---|---|---|
| Lower | Upper | ||||
| Primary | |||||
| HbA1c (%) | 8 (2.1) | 6.4 (0.9) | 0.2 | 0.1 | 0.28 |
| Secondary | |||||
| Fitness (watts/kg; n=13) | 1.36 (0.33) | 1.21 (0.3) | 0.14 | −0.04 | 0.33 |
| BMI (kg/m2) | 36.8 (6.6) | 36.1 (5.5) | 0.01 | −0.03 | 0.06 |
| Percent fat mass | 44.1 (9.4) | 44.5 (6.8) | 0.19 | −0.06 | 0.09 |
| Cholesterol (mmol/L) | 4.4 (0.97) | 4.9 (1.3) | −0.07 | −0.19 | 0.04 |
| Triglycerides (mmol/L) | 2.35 (1.82) | 2.85 (2.0) | −0.12 | −0.40 | 0.15 |
| HDL (mmol/L) | 0.88 (0.15) | 0.95 (0.15) | −0.09 | −0.19 | 0.01 |
| LDL (mmol/L) | 2.86 (1.15) | 3.3 (1.10) | −0.13 | −0.31 | 0.04 |
| ALT (units/L) | 61.0 (55.0) | 40.7 (18.3) | 0.26 | −0.10 | 0.61 |
| ACR (n=15) | 7.3 (15.6) | 10.4 (19.1) | 0.06 | −0.62 | 0.74 |
| C-peptide (pmol/L) | 2,518 (1,250) | 2,120 (848) | 0.22 | 0.07 | 0.38 |
Abbreviations: HbA1c, glycated hemoglobin; BMI, body mass index; HDL, high-density lipoprotein; LDL, low-density lipoprotein; ALT, alanine aminotransferase; ACR, albumin to creatinine ratio; C-peptide, endogenous insulin; SD, standard deviation; CI, confidence interval.