Skip to main content
. 2014 Jul 22;15(1):624. doi: 10.1186/1471-2164-15-624

Table 2.

Summary of spatiotemporal microarray profiling of 41 DEGs found in the triplicated segment of MMU16

Full gene name (Official gene symbol) Probe set ID Log 2 expression of Ts1Cje normalized against disomic littermates
Cerebral cortex Cerebellum Hippocampus
P1 P15 P30 P84 P1 P15 P30 P84 P1 P15 P30 P84
RIKEN cDNA 1110004E09Rik gene (1110004E09Rik) 1424315_at 0.72 0.70 0.67 0.73 1.39* 0.91 0.91 0.70 0.61 1.12 0.97 0.83
RIKEN cDNA 2410124H12Rik gene (2410124H12Rik) 1432515_at 0.03 0.09 0.01 0.16 0.07 1.68** 1.51*** 2.26*** -0.02 -0.08 0.05 -0.14
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (Atp5o) 1416278_a_at 0.65 0.49 0.70 0.48 0.43 0.67 0.82* 0.54 0.68 0.37 0.48 1.09***
1437164_x_at 0.58 0.71 0.72* 0.64 0.68* 0.74** 0.78** 0.59 0.71* 0.64* 0.74* 0.94***
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 (B3galt5) 1450528_at 0.00 0.02 -0.02 0.00 0.02 0.15 -0.01 0.43 -0.02 -0.11 0.15 1.25*
Expressed sequence BF642829 (BF642829) 1435484_at 0.56 0.34 0.68 -0.04 0.91** 0.75* 0.68 0.01 0.59 0.69 0.89** 0.17
Bromodomain and WD repeat domain containing 1 (Brwd1) 1427322_at 0.67 0.45 0.50 0.40 0.32 0.81* 0.84* 0.54 0.78 0.26 0.52 1.11***
1433955_at 0.55 0.53 0.63 0.86* 1.17*** 0.81** 0.57 1.01*** 0.39 0.70* 0.70* 0.91***
1452322_a_at 0.07 0.62 0.47 0.83* 0.14 0.37 0.22 0.94*** 0.67* 0.46 0.68* 0.22
C2 calcium-dependent domain containing 2 (C2cd2) 1436344_at 0.47 0.47 0.38 0.54 0.27 1.87*** 0.47 0.74 0.39 0.71 0.91 0.68
1437731_at 0.79 0.30 0.15 0.47 0.59 1.21* 0.18 0.45 0.58 0.32 0.55 0.18
Carbonyl reductase 1 (Cbr1) 1460196_at 0.67 0.48 0.66 0.58 0.71 0.52 0.30 0.72* 0.64 0.95** 0.72 0.74*
Carbonyl reductase 3 (Cbr3) 1427912_at 1.55 1.11 0.82 0.81 1.08 -0.02 0.21 0.79 1.24 2.04* 1.07 0.44
Chromatin assembly factor 1, subunit B (p60) (Chaf1b) 1423877_at 1.15*** 0.10 0.00 0.08 0.93*** -0.03 -0.06 0.00 1.51*** 0.05 -0.08 -0.11
Crystallin, zeta (quinone reductase)-like 1 (Cryzl1) 1430547_s_at 0.70 0.57 0.76 0.55 0.60 0.70 0.97 0.94* 0.57 0.17 0.37 1.28***
1451473_a_at 0.47 0.61 0.86** 0.67 0.61 0.88*** 0.49 0.51 0.57 0.82** 0.85** 0.59*
DnaJ (Hsp40) homolog, subfamily C, member 28 (Dnajc28) 1420542_at 0.36 0.29 0.14 0.18 0.26 0.33 0.21 0.81* 0.28 0.15 0.26 0.23
Downstream neighbor of SON (Donson) 1426739_at 0.76 0.72 0.91** 0.78 0.82* 0.91** 0.75 0.75* 0.81* 0.65 0.63 0.92**
Dopey family member 2 (Dopey2) 1428330_at 0.68* 0.47 0.61 0.45 0.58 0.83** 0.70* 0.59 1.00*** 0.68* 0.85** 0.77**
Down syndrome cell adhesion molecule (Dscam) 1441082_at 0.35 0.70 1.13 0.78 0.41 0.36 0.94 0.74 0.40 1.60** 1.13 0.59
1449411_at 0.94 0.83 0.98 1.03 0.69 0.54 0.70 1.22* 0.81 1.52** 0.87 0.86
1458625_at 0.52 0.44 0.74 0.72 0.79 0.11 0.33 0.50 0.72 1.65*** 1.39** 0.45
Down syndrome critical region 3 (Dscr3) 1415745_a_at 0.87 0.74 0.66 0.91 0.97* 0.93* 0.87 0.66 0.80 0.89* 1.01* 0.94*
E26 avian leukemia oncogene 2, 3' domain (Ets2) 1416268_at 0.78 0.62 0.81 0.56 0.54 0.87* 0.65 0.80* 0.62 0.45 0.68 0.77
Phosphoribosylglycinamide formyltransferase (Gart) 1416283_at 0.52 0.38 0.92 0.37 0.39 1.17** 0.54 0.93 0.70 0.95 1.20* 0.95
1424436_at 0.41 0.85 0.70 0.98 0.98 1.03* 0.20 1.30*** 0.18 0.93 0.69 0.67
High mobility group nucleosomal binding domain 1 (Hmgn1) 1422495_a_at 0.51 0.60 0.59 0.55 0.22 0.96** 0.49 0.68* 0.36 0.16 0.64 0.82**
1438940_x_at 0.39 0.52 0.50 0.67 0.40 0.76* 0.24 0.54 0.39 0.33 0.50 0.36
1455897_x_at 0.44 0.69 0.70 0.95 0.49 1.07** 0.30 0.80 0.40 0.52 0.87 0.58
Hormonally upregulated Neu-associated kinase (Hunk) 1418260_at 0.66 0.66 0.25 0.68 0.41 0.83 0.87 0.64 1.10* 0.52 0.61 1.16**
Interferon (alpha and beta) receptor 1 (Ifnar1) 1442222_at 0.63 0.74 1.05 0.77 0.45 1.12* 0.73 0.68 0.62 0.80 0.80 0.75
1449026_at 0.80 0.80 1.17* 1.29* 0.55 0.67 0.85 1.10* 0.46 1.12* 0.84 0.75
Interferon (alpha and beta) receptor 2 (Ifnar2) 1427691_a_at 0.66 0.52 0.67 0.40 0.55 0.80 0.48 0.58 0.73 1.49* 0.91 0.50
1440169_x_at 0.72 0.92 0.78 0.60 0.89 0.68 0.45 0.34 1.22 1.49* 0.84 0.62
1451462_a_at 0.70 0.90 0.99* 0.98 0.61 0.90* 0.80 0.93* 0.81 0.83 0.92* 1.43***
Interferon gamma receptor 2 (Ifngr2) 1423558_at 0.31 0.39 0.40 0.44 0.67** 0.14 0.17 0.21 0.21 0.45 0.28 0.26
Intersectin 1 (SH3 domain protein 1A) (Itsn1) 1421192_a_at 0.82 0.45 0.90 0.40 0.03 0.94* 1.16** 0.66 1.01* 0.48 0.97* 1.04**
1425899_a_at 0.58 0.61 0.71 0.22 0.35 0.72 1.37 0.90 0.76 -0.54 0.18 1.67*
1435885_s_at 0.56 0.61 0.63 0.66** 0.46 1.18* 0.25 0.50 0.49 0.37 0.97 0.21
1452338_s_at 0.58 0.96 1.42** 1.66 0.44 0.99 0.80 1.30** 0.64 0.25 0.70 0.74
Potassium inwardly-rectifying channel, subfamily J, member 6 (Kcnj6) 1425707_a_at -0.13 0.24 0.22 0.59 0.18 0.29 0.04 0.31 -0.21 0.57 1.07* -0.06
Microrchidia 3 (Morc3) 1420091_s_at 0.55 0.81** 0.64 0.66 0.78** 0.84*** 0.69* 0.55 0.64* 0.66* 0.78** 0.99***
1452224_at 0.69 0.64 0.68 0.66 0.82 0.99 1.21* 0.52 1.20* 0.51 0.55 1.45**
Mitochondrial ribosomal protein S6 (Mrps6) 1424440_at 0.84** 0.62 0.73 0.35 0.89** 0.70* 0.89** 1.00*** 0.77* 0.72* 0.64 0.91**
1447585_s_at 0.93 0.74 0.88 0.74 1.13* 0.88 0.53 0.94 0.61 1.15* 0.91 0.61
PAX3 and PAX7 binding protein 1 (Paxbp1) 1418007_at 0.55 0.66 0.75 0.59 0.55 1.32* 0.59 0.80 0.83 0.15 0.80 0.56
1418008_at 0.46 0.38 0.74 0.62 0.56 1.45* 0.63 0.75 0.92 0.21 0.92 0.86
Phosphatidylinositol glycan anchor biosynthesis, class P (Pigp) 1436038_a_at 0.69* 0.70 0.77* 0.95** 0.77** 0.75** 0.84** 0.82*** 0.38 0.54 0.55 1.16***
PR domain containing 15 (Prdm15) 1455459_at 0.41 -0.04 0.47 0.59 0.21 0.37 0.59 0.18 0.44 0.48 0.35 0.95*
Proteasome (prosome, macropain) subunit, alpha type 2 (Psmg1) 1448307_at 0.81* 0.52 0.78 0.97* 0.73 0.99** 0.57 0.88** 0.55 1.04** 0.82* 0.94**
Regulator of calcineurin 1 (Rcan1) 1416600_a_at 0.98* 0.74 0.89 0.43 0.89 0.71 0.70 0.76 0.73 1.10** 0.84 0.68
Receptor-interacting serine-threonine kinase 4 (Ripk4) 1418488_s_at 0.06 0.07 0.00 0.12 0.12 -0.02 0.06 0.02 0.53*** 0.02 -0.05 -0.09
Solute carrier family 5 (inositol transporters), member 3 (Slc5a3) 1435484_at 0.56 0.34 0.68 -0.04 0.91*** 0.75*** 0.68 0.01 0.59 0.69 0.89*** 0.17
Small integral membrane protein 11(Smim11) 1417402_at 0.85 0.43 0.64 0.40 0.90* 0.69 0.59 0.59 0.77 0.37 0.68 0.70
Son cell proliferation protein (Son) 1420952_at 0.68 0.69 0.90 0.86 0.36 1.28* 0.71 0.87 0.88 0.54 0.77 0.65
1435862_at 0.64 0.75 0.80 0.63 0.35 1.04** 1.24*** 0.78 0.99* 0.20 0.58 1.17**
1437924_at 0.63 0.62 0.79 0.82 0.28 0.96** 0.75 0.67 0.35 0.60 0.65 0.73
Synaptojanin 1 (Synj1) 1436333_a_at 0.67 0.65 0.77 0.84 0.89 0.57 0.74 0.84 0.74 1.38* 0.79 0.72
1454961_at 0.60 0.57 0.65 0.63 0.57 0.43 0.58 0.71* 0.56 0.86** 0.55 0.67
Transmembrane protein 50B (Tmem50b) 1423707_at 0.78** 0.51 0.70* 0.46 0.83** 0.69* 1.07*** 0.71** 0.96*** 0.76** 0.84** 0.99***
Tetratricopeptide repeat domain 3 (Ttc3) 1416484_at 0.52 0.53 0.68 0.56 0.60 0.39 0.74 0.87* 0.53 0.31 0.26 0.78
1448361_at 0.45 0.45 0.54* 0.43 0.21 0.43 0.46 0.40 0.33 0.63** 0.45 0.46
URB1 ribosome biogenesis 1 homolog (S. cerevisiae) (Urb1) 1454841_at 0.58 0.49 0.77 0.46 0.24 0.16 0.48 0.37 0.98* 0.62 0.76 0.85
Tryptophan rich basic protein (Wrb) 1460446_at 0.62 0.64 0.63 0.74 0.72* 0.90* 0.45 0.67* 0.56 0.85** 0.69 0.70*

*p<0.05, **p<0.01 and ***p<0.001 based on Empirical Bayes t-statistic test.