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. 2014 Jul 25;14:753. doi: 10.1186/1471-2458-14-753

Figure 3.

Figure 3

Envisioned benefits of the pathogen niche approach. Public health strategies are generally conditioned by an economic constraint in low-income countries whereas they target maximal burden alleviation for high-income countries. Methods for pathogen control are known to make things worse than doing nothing if coverage is below a given threshold (e.g., insufficient vaccine uptake against childhood infections may postpone infections to teenage years when the disease has higher morbidity). Combining different methods for pathogen control (e.g., vaccination tuned along the spatio-temporal dynamics of the pathogen in addition to quarantine) can decrease the risk of unexpected backfires of public health programs and offer greater public health benefits for similar cost.