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The IFN dose until 24 weeks according to platelet count. The actual IFN dose rate until 24 weeks was evaluated as less than 50, 50–80, and 80 % of the normal dose. Group A, chronic hepatitis (plt ≥8); group B, chronic hepatitis (plt <8); group C, untreated cirrhosis group (plt ≥8); group D, untreated cirrhosis group (plt <8); group E, splenectomy/PSE
