Table 1.
Laboratory characteristics of patients investigated according to the stage of disease1
| Stage | I | II | III | IV |
| Patients (n°) | 12 | 11 | 15 | 13 |
| Alkaline phosphatase (U/L | 273 (50-797) | 447 (145-1315) | 397 (190-1956) | 289 (52-1960) |
| AST (U/L) | 28 (13-6) | 38 (25-400) | 35 (14-63) | 49 (11-144) |
| ALT (U/L) | 37 (14-89) | 54 (17-100) | 39 (17-72) | 47 (8-218) |
| Total Bilirubin (mg/dL) | 0.7 (0.4-2.4) | 0.9 (0.2-1.2) | 0.9 (0.3-1.5) | 1.0 (0.5-1.6) |
| Cholesterol (mg/dL) | 190 (112-235) | 220 (104-285) | 219 (110-275) | 208 (154-314) |
| aPTT (sec) | 32 (27-63) | 28 (26-43) | 32 (25-37) | 32 (26-36) |
| PT (%) | 98 (90-105) | 100 (91-120) | 99 (81-100) | 93 (58-100) |
| Fibrinogen (mg/dL) | 379 (279-650) | 380 (268-463) | 327 (276-590) | 380 (100-586) |
1Data are expressed as median (range).