Table 2.
Platelet and blood coagulation tests
| PBC patients n = 51 | Controls n = 102 | |
| Sonoclot RATE (U/min) all pts | 29 (14-49)b | 21 (14-31) |
| • <150 x 103/μL plts (n = 22) | 30 (14-49)b | |
| • ≥150 x 103/μL plts (n = 29) | 28 (19-41)d | |
| Sonoclot TP (min) all pts | 12 (6-30)d | 9 (6-15) |
| • <150 x 103/μL plts (n = 22) | 15 (6-30)d | |
| • ≥150 x 103/μL plts (n = 29) | 10 (6-24) | |
| PFA/EPI - CT (secs) | 151.5 (60-222) | 146 (111-179) |
| [≥150 x 103/μL plts (n = 29)] | ||
| PFA/ADP- CT (secs) | 106 (61-180) | 102 (61-148) |
| [≥150 x 103/μL plts (n = 29)] | ||
| TAT (μg/L) | 2.8 (1.5-87.3)b | 2.5 (1.1-4.2) |
| D-Dimer (ng/mL) | 16.0 (2-173) | 23.0 (3-55) |
| TF (pg/mL) | 255.6 (24.8-466.1)d | 121.9 (24.8-466.1) |
| TM (μg/mL) | 23.7 (2.6-153.5)d | 13.8 (7.6-23.1) |
b
P < 0.01,
d
P < 0.001 vs Controls; TP = time to peak; PFA/EPI - CT = closure time with epinephrine; PFA/ADP-CT = closure time with ADP. Data are expressed as median (range).