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. 2006 Mar 21;12(11):1671–1680. doi: 10.3748/wjg.v12.i11.1671

Table 2.

"p53" mutation in gastric cancers of early stages and precancerous gastric lesions. In gastric cancers of early stages and precancerous gastric lesions, LOH and splicing are merely reported. Abbreviations for mutation: Del: deletion; Ins: insertion; F/S: frame shift. Abbreviations for lesion: EGC: early gastric cancer; AD: adenoma, CA/AD: carcinoma in adenoma; D: dysplasia; IM: intestinal metaplasia; N: mucosa without dysplasia, IM or carcinoma. Data are collected from references 104, 105, 113-118. (Modified from Tsuji et al[119,120])

First author Year Case G:CA:T G:CT:A A:TG:C A:TC:G A:TT:A G or C Del Ins F/S Lesions
Yokozaki 1992 1 2 1 1 1 EGC
Tohdo 1993 5 3 1 AD or CA/AD
Uchino 1993 12 10 2 1 EGC
Correa 1994 8 4 3 1 D, IM, or N
Hongyo 1995 9 10 1 1 2 Cancer at stage I
Sakurai 1995 7 4 AD, CA/AD or EGC
Tamura 1995 1 1 AD
Tamura 1995 4 3 2 EGC
Ranzani 1995 18 13 1 1 1 1 2 EGC
Summary 45 3 8 3 2 3 4 4 1
(%) 62 4 11 4 3 4 5 5 1