Table 1.
Clinical, biochemical and serological features of the four H63D homozygous patients
| Case 1 | Case 2 | Case 3 | Case 4 | |
| Age (yr) | 36 | 35 | 44 | 66 |
| BMI (kg/m2) | 30 | 24 | 32.5 | 31 |
| Blood pressure (mmHg) | 140/100 | 130/80 | 160/100 | 150/95 |
| Alcohol intake (g/wk) | 8 | 0 | 60 | 0 |
| Blood sugar (mmol/L) | 4.2 | 4.6 | 5.6 | 9.5 |
| Total cholesterol (mmol/L) | 4.1 | 4.3 | 5.5 | 6 |
| Triglicerides (mmol/L) | 1.6 | 1.5 | 3.6 | 2.9 |
| AST (U/L) | 46 | 69 | 44 | 15 |
| ALT (U/L) | 117 | 175 | 112 | 18 |
| γGT (U/L) | 50 | 45 | 70 | 30 |
| Ferritin (µg/L) | 454 | 350 | 568 | 423 |
| HCV/HBV serology | neg | neg | neg | neg |
Legend: BMI=body mass index; wk=week; neg=negative. Normal ranges: BMI 18 - 25 kg/m2; blood pressure max < 120mmHg, min<80mmHg (see the seventh report of the Joint National Committee on high blood pressure, NIH publication no 03 - 5233, December 2003); blood sugar < 6mmol/L.