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. Author manuscript; available in PMC: 2014 Aug 7.
Published in final edited form as: J Huntingtons Dis. 2013 Jan;2(4):443–451. doi: 10.3233/JHD-130074

Fig. 2.

Fig. 2

C2-8 treatment does not show a significant rescue effect on behavioral deficits in R6/2 mice. (A) Rotarod performance of C2-8-treated and vehicle-treated R6/2 mice at 5, 8, and 11 weeks of age. C2-8-treated mice performed similar to vehicle controls on the Rotarod at all three time points (drug effect: F(2,70) = 0.29, P value = 0.7483). (B) Wire-hang endurance of R6/2 mice showed no improvement at 9.5 and 12.5 weeks of age with C2-8 treatment (F(2,35) = 0.14, P value = 0.8738). Values represent mean ± S.E.M. Vehicle: n = 11; C2-8 10 m/kg: n = 14; C2-8 20 mg/kg: n = 13. Data were analyzed with repeated measure two-way ANOVA.