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. Author manuscript; available in PMC: 2014 Aug 7.
Published in final edited form as: J Huntingtons Dis. 2013 Jan;2(4):443–451. doi: 10.3233/JHD-130074

Fig. 6.

Fig. 6

C2-8 treatment leads to significant reduction of mutant huntingtin aggregate volume in R6/2 mouse striatum. (A) Representative immunodetection of intraneuronal mutant huntingtin aggregates using EM48 antibody in the neostriatum of 13-week-old R6/2 mice with vehicle or 20 mg/kg C2-8 treatment (scale bar = 25 μm). (B) C2-8 treatment significantly reduced the striatal intranuclear aggregate volume in R6/2 mice (F(2,27) = 9.339, = 0.0008). Values represent mean ± S.E.M., n = 10; **P < 0.01, ***P < 0.001, one-way ANOVA followed by Tukey post-test.