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. 2014 Aug 7;4:5978. doi: 10.1038/srep05978

Figure 6. The role of IKK in VEGF and HGF production in cardiomyocytes under hypoxic conditions.

Figure 6

(a) Representative immunoblots of VEGF and HGF in p27kip1-knockdown H9c2 cells treated with IKKα or IKKβ siRNA and then exposed to hypoxia for 3 h. GAPDH served as the loading control. Quantification is shown, *p < 0.05 versus p27 knockdown IKKα/IKKβ inhibitor 0 h; #p < 0.05 versus IKKα/IKKβ inhibitor 3 h (n = 3). (b) Representative immunoblots of VEGF and HGF in p27kip1-knockdown H9c2 cells treated with the pharmacological IKK inhibitor, ACHP, and then exposed to hypoxia for 3 h. GAPDH served as the loading control. Quantification is shown, *p < 0.05 versus p27 knockdown (n = 3).