Table 2.
Incidences of PONV and rescue antiemetics
| Group A (n = 41) | Group B (n = 44) | Group C (n = 42) | P value | |
|---|---|---|---|---|
| Postoperative 0–48 h |
|
|
|
|
| Nausea |
24 (59) |
18 (41) |
6 (14) † ‡ |
< 0.001 |
| Retching & Vomiting |
9 (22) |
9 (20) |
3 (7) |
0.13 |
| Complete response |
15 (37) |
26 (59) |
35 (83) † |
< 0.001 |
| Rescue antiemetic |
11 (27) |
9 (20) |
1 (2) † ‡ |
0.008 |
| Postoperative 0–2 h |
|
|
|
|
| Nausea |
6 (15) |
5 (11) |
2 (5) |
0.318 |
| Retching & Vomiting |
1 (2) |
1 (2) |
1 (5) |
0.999 |
| Complete response |
34 (83) |
40 (91) |
40 (95) |
0.172 |
| Rescue antiemetic |
2 (5) |
3 (7) |
0 (0) |
0.249 |
| Postoperative 2–24 h |
|
|
|
|
| Nausea |
17 (41) |
12 (27) |
3 (7) † ‡ |
0.001 |
| Retching & Vomiting |
6 (15) |
8 (18) |
2 (2) |
0.154 |
| Complete response |
23 (56) |
33 (75) |
38 (86) † |
0.002 |
| Rescue antiemetic |
8 (20) |
5 (11) |
1 (2) † |
0.045 |
| Postoperative 24–48 h |
|
|
|
|
| Nausea |
16 (39) |
14 (32) |
4 (10) † |
0.006 |
| Retching & Vomiting |
4 (10) |
5 (11) |
0 (0) |
0.088 |
| Complete response |
25 (61) |
30 (68) |
38 (90) † |
0.006 |
| Rescue antiemetic | 5 (12) | 6 (14) | 0 (0) | 0.050 |
Group A; ondansetron 4 mg group. Group B; ondansetron 8 mg group. Group C; ramosetron 0.3 mg group. Values are expressed as number of the patients (%). †: <0.0175 compared with Group A. ‡: 0.0175 compared with Group B.