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. Author manuscript; available in PMC: 2014 Aug 7.
Published in final edited form as: Adv Drug Deliv Rev. 2007 Aug 14;59(13):1329–1339. doi: 10.1016/j.addr.2007.08.007

Table 2. Subset of extracellular ligands and their respective binding proteins [37].

Ligand Matrix association Cell receptor Tissue location
Collagen I Collagen, fibronectin Integrin ECM, tendons, bone, skin
Collagen IV Laminin Integrin Basal lamina
Fibronectin Collagen, fibrin, heparin, fibullin, syndecan Integrin ECM, especially wound healing process
Elastin Tropoelastin, fibrillin ECM, especially arteries
Laminin Laminin, collagen IV Integrin Epithelium, endothelium, basal lamina
HHS Vulnerability Disclosure