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. 2013 Oct 8;8(1):83–92. doi: 10.1016/j.molonc.2013.09.004

Figure 2.

Figure 2

Pre‐miR‐203 induced oxaliplatin resistance in HT29 cells. A. miR‐203 expression level was significantly increased after transient transfection of pre‐miR‐203 in HT29 cells as measured by qPCR. B. Overexpression of miR‐203 induced by pre‐miR‐203 transfection significantly decreased the growth‐inhibitory effect of oxaliplatin in HT29 cells, as measured by MTT assay. C. The apoptosis‐inducing effect of oxaliplatin (Oxali) at 48 h post treatment, as reflected by induction of cleaved PARP and caspase‐3 (Casp3) by Western blotting. The effect was partially blocked by overexpression of miR‐203 through transient transfection of pre‐miR‐203 in HT29 cells. *P < 0.05. Results are representative of three experiments.