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. Author manuscript; available in PMC: 2014 Aug 7.
Published in final edited form as: Am J Surg Pathol. 2012 Aug;36(8):1216–1221. doi: 10.1097/PAS.0b013e318254ce54

FIGURE 3.

FIGURE 3

Immunohistochemistry in sinonasal NMCs. A, One of the sinonasal NMCs focally expressed neuroendocrine markers (chromogranin immunohistochemistry), as well as (B) S100 protein (S100 immunohistochemistry). C, Each sinonasal NMC was strongly and diffusely immunoreactive with NUT, a protein expressed only in NMC and germ cells (NUT immunohistochemistry). The pattern of expression was similar to that seen in the spermatids of non-neoplastic testis (inset; NUT immunohistochemistry). D, However, NUT expression was weak or even negative in the areas of overt squamous differentiation (NUT immunohistochemistry).