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Immunohistochemical Profile of NMCs
| Cases | Original Diagnosis | Immunohistochemical Staining
|
|||||||
|---|---|---|---|---|---|---|---|---|---|
| NUT | AE1/AE3 | p63 | EMA | CD34 | SYN | CHR | S100 | ||
| 1 | SNUC | + | + | − | + | − | − | − | − |
| 2 | SNUC | + | + | + | F | + | F | F | F |
| 3 | SqCC | + | + | + | F | − | − | − | − |
CHR indicates chromogranin; EMA, epithelial membrane antigen; F, focal immunoexpression (ie, <5% of tumor cells); SqCC, poorly differentiated squamous cell carcinoma; SYN, synaptophysin.
