Table 1. Demographic and Clinical characteristics of the study patients.
| Surgical (n=79) | Medical (n=39) | p | SO (n=10) | S+rt-PA (n=69) | p | |
|---|---|---|---|---|---|---|
| Symptom Onset Age (years) | 60.6 (11.5) | 61.0 (12.4) | 0.87 | 68.9 (9.2) | 59.4 (11.4) | 0.01 |
| Enrollment GCS | 10.1 (2.9) | 10.4 (3.8) | 0.67 | 11.5 (2.8) | 9.8 (2.9) | 0.09 |
| % Male | 53 (67.1%) | 26 (66.7%) | 1.00 | 6 (60.0%) | 47 (68.1%) | 0.72 |
| Race | 0.60 | 0.81 | ||||
| Caucasian | 44 (55.7%) | 21 (53.8%) | 7 (70.0%) | 37 (53.6%) | ||
| African American | 25 (31.6%) | 10 (25.6%) | 2 (20.0%) | 23 (33.3%) | ||
| Hispanic | 9 (11.4%) | 5 (12.8%) | 1 (10.0%) | 8 (11.6%) | ||
| Asian or Pacific Islander | 1 (1.3%) | 2 (5.1%) | 0 (0.0%) | 1 (1.4%) | ||
| Unknown | 0 (0.0%) | 1 (2.6%) | 0 (0.0%) | 0 (0.0%) | ||
| Clot Location | 0.22 | 0.10 | ||||
| Thalamus | 4 (5.1%) | 1 (2.6%) | 0 (0.0%) | 4 (5.8%) | ||
| Putamen | 46 (58.2%) | 24 (61.5%) | 3 (30.0%) | 43 (62.3%) | ||
| Lobar | 22 (27.8%) | 14 (35.9%) | 6 (60.0%) | 16 (23.2%) | ||
| Globus Pallidus | 7 (8.9%) | 0 (0.0%) | 1 (10.0%) | 6 (8.7%) | ||
| CNS Infection* | 2 (2.5%) | 1 (2.6%) | 1.00 | 0 (0.0%) | 2 (2.9%) | 1.00 |
| Symptomatic Bleed* | 3 (3.8%) | 0 (0.0%) | 0.55 | 0 (0.0%) | 3 (4.3%) | 1.00 |
| Emergent ICP Therapy† | 14 (17.7%) | 10 (25.6%) | 0.34 | 1 (10.0%) | 13 (18.8%) | 0.68 |
| Emergent Osmotherapy | 10 (12.7%) | 9 (23.1%) | 0.18 | 1 (10.0%) | 9 (13.0%) | 1 |
SO, Surgery only; S+tPA, Surgery + rt-PA; CNS, central nervous system,
*
within analysis window of BLS to EOT;
†
ICP Therapy included Osmotherapy, Aggressive Hyperventilation, and Surgical Decompression