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. 2014 Jul 17;2014:389048. doi: 10.1155/2014/389048

Table 1.

Dosimetric reduction in normal tissue radiation for proton- versus photon-based SABR plans.

Author, reference Number of plans compared (n) Total dose, GyE (dose per fraction) Lung reduction from protons Esophagus reduction from protons
Hoppe et al., [25] 16 48 (12) Mean dose 2.2 GyE
V5, 10.4%∗ 
V10, 6.4%
V20, 2.1%

Seco et al., [26] 20 42 (14) V5, 37.8% Maximum dose, 68%

Georg et al., [27] 36 45 (15) V20, PSPT, 7–9%
V20, IMPT, >10%

Register et al., [6] 45 50 (12.5) Mean dose, 50%

Kadoya et al., [29] 21 66 (6.6) Mean dose 2.8 GyE
V5, 18.8%
V10, 10.4%
V20, 2.3%

*Vx: percentage of structure volume receiving ≥X GyE. PSPT: passively scattered proton therapy. IMPT: intensity-modulated proton therapy.