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. 2014 Jul 29;11:21. doi: 10.1186/1742-6405-11-21

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Copyright © 2014 Basso et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Study design overview. Initial Follow-Up (IFU) started at T1 (in 2009) and lasted 2 years, Final Follow-Up (FFU) started at the end of IFU, lasted one year and finished at T2, in 2012.