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Mechanism of cell death determined by Annexin flow cytometry. MDA-MB −435 (left) and MDA-MB-231 cells (right) 48 hours after photochemical internalization (PCI) (18 hours, 1 μg/mL phthalocyanine disulfonate, 1 hour cisplatin [CP] or dichloro(4,4′-dipropyl-2,2′-bipyridine) platinum [DP]). The predominant mechanism of cell death is apoptotic. PDT, photodynamic therapy.
