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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Mol Cancer Ther. 2013 Aug 20;12(10):2006–2017. doi: 10.1158/1535-7163.MCT-13-0239

Figure 1. Effect of 13-197 on therapy-resistant MCL cells growth/proliferation in-vitro.

Figure 1

Ten thousand of each MCL cells indicated were cultured in RF-10 media containing 1, 5, 10 and 20 μM 13-197 in 96-well plates for 24, 48 and 72 hours. A: shows the chemical structure and molecular properties of 13-197. B–G: MTT assay was used to determine the cell viability in control and treated cells. The values represent the means ± SD from four wells of the 96-well plates. H–M: The proliferation levels of control and treated cells were determined using 3[H]-thymidine uptake method. The values represent the means ± SD from triplicate wells of the 96-well plates. Similar results were obtained from three sets of independent experiments. * -and *** indicate the significance at p<0.01 and p<0.001, respectively.