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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Mol Cancer Ther. 2013 Aug 20;12(10):2006–2017. doi: 10.1158/1535-7163.MCT-13-0239

Figure 2. Effect of 13-197 on therapy-resistant MCL cells morphology/apoptosis.

Figure 2

Exponentially growing therapy-resistant and other MCL cells were treated with 10 μM 13-197 for 48 hours. Following treatment, cells were stained with Wright-Giemsa staining using a cytospin preparation. The cells were examined under bright field microscope for the apoptotic cells and images were captured at 40X magnification; A: cytomorphology of different MCL cells indicated above following treatment with 13-197 specifically examining apoptotic bodies; B: Annexin-V apoptosis detection assay was used to access percent of cells undergoing apoptosis in those MCL cell lines following treatment with 10 μM 13-197 for 48 hours. The values represent the means ± SD of three separate experiments.