Table 3.
Particulars | Control (Group I) | DEN + Fe-NTA (Group II) | DEN & Fe-NTA + plant extract (200 mg/kg) (Group III) | DEN & Fe-NTA + plant extract (400 mg/kg) (Group IV) | Plant extract alone (200 mg/kg) (Group V) | Plant extract alone (400 mg/kg) (Group VI) | DEN & Fe-NTA + Std drug (GroupVII) |
---|---|---|---|---|---|---|---|
Lipid peroxidation in liver | 1.56 ± 0.06a | 4.95 ± 0.14b | 2.56 ± 0.08c | 1.74 ± 0.09d | 1.58 ± 0.06a | 1.54 ± 0.06a | 1.59 ± 0.06a |
SOD | 11.08 ± 0.46a | 6.19 ± 0.30b | 9.96 ± 0.23c | 10.92 ± 0.54a | 11.39 ± 0.22a | 12.62 ± 0.28a | 10.41 ± 0.42a |
Catalase | 6.01 ± 0.05a | 3.25 ± 0.26b | 4.33 ± 0.08c | 6.04 ± 0.09a | 5.96 ± 0.07a | 6.19 ± 0.07a | 6.03 ± 0.03a |
PX | 40.22 ± 0.59a | 16.85 ± 0.91b | 35.64 ± 0.16c | 39.33 ± 0.65d | 39.30 ± 0.38d | 38.94 ± 0.4d | 39.19 ± 0.34d |
GST | 131.22 ± 2.7a | 98.08 ± 2.84b | 112.86 ± 2.62c | 130.07 ± 0.60a | 130.66 ± 1.27a | 132.56 ± 0.65a | 131.08 ± 1.99a |
G6PD | 13.95 ± 0.11a | 5.46 ± 0.24b | 8.67 ± 0.09c | 13.51 ± 0.4a | 13.8 ± 0.21a | 13.88 ± 0.12a | 13.7 ± 0.18a |
GPx | 43.94 ± 0.34a | 21.58 ± 0.59b | 30.64 ± 0.24c | 45.06 ± 0.59d | 45.54 ± 0.44d | 46.59 ± 0.39e | 46.16 ± 0.7e |
Values are expressed as mean ± SD (n = 6).
Values not sharing the common superscript differ significantly (DMRT).
Units are as follows: SOD—unit/mg protein; CAT—µ moles of H2O2 consumed/min/mg protein;
Px—units/g tissue:
LPO—nmoles of MDA formed/mg protein.