Table 2.
Author and year | N | Original diagnosis for RT | Mean age (yrs.)∗ | F/M | Mean RT dose (Gy) | Mean latency (yrs.) | Histology | WHO grade | Mean follow-up (yrs.) | Recurrence |
---|---|---|---|---|---|---|---|---|---|---|
Harrison et al., 1991 [5] | 7 | 2, tinea capitis 1, presumed sarcoma 1. prepubertal gigantism 1, thalamic glioma 1, keloid 1, astrocytoma |
53.4 | 5/2 | — | 42.7 | 3, atypical 2, meningothelial 1, transitional 1, mixed (meningothelial, transitional, fibroblastic) |
— | — | 3 (42.9%) |
| ||||||||||
Salvati et al., 1996 [29] | 10 | 4, ALL 2, medulloblastoma 2, adenoma 1, carcinoma 1, astrocytoma |
30.4 | 7/3 | 39.8 | 16.9 | 4, atypical 4, fibroblastic 1, meningothelial 1, transitional |
— | — | 1 (10%) |
| ||||||||||
Sadetzki et al., 2002 [30] | 253† | 253, tinea capitis | 43.6 | 1.9 : 1 | — | 36.3 | 183, NOS 63, meningothelial 38, transitional 31, fibroblastic 4, angioblastic 2, psammomatous 1, malignant 6, mixed |
— | 9.8 | 18.2% |
| ||||||||||
De Tommasi et al., 2005 [31] | 6 | 6, tinea capitis | 57.7 | 4/2 | 15 | 40.2 | 2, meningothelial 2, transitional 1, choroid 1 atypical |
4, I 2, II |
— | 0 |
| ||||||||||
Banerjee et al., 2009 [32] | 8 | 8, ALL | 26.5 | 5/3 | 26.5 | 23 | 3, meningothelial 2, fibroblastic 2, transitional 1, atypical |
7, I 1, II |
— | 2 (25%) |
| ||||||||||
Godlewski et al., 2012 [33] | 19 | 4, ALL 3, NHL 3, astrocytoma 2, ependymoma 1, pituitary adenoma 1, medulloblastoma 1, “brain tumor” 1, CNS lymphoma 1, leukemia 1, germinoma 1, ganglioneuroblastoma |
35.7 | 12/7 | 31.9 | 25.9 | — | 17, I 1, II 1, N/A |
5.8 | 4 (21.1%) |
*Age at diagnosis of radiation-induced meningioma.
†220/253 patients were treated by surgical resection.
ALL: acute lymphoblastic leukemia; N/A: not available; NHL: non-Hodgkin's lymphoma; NOS: not otherwise specified; RT: radiation therapy.