Fig. 1.
The effect of inhibition of 20-hydroxyeicosatetraenoic acid (20-HETE) production on proximal straight tubule (PST) transport. During the experimental period, 10−6 M N-methylsulfonyl-12,12-dibromododec-11-enamide (DDMS) was added to the bath (n = 3). DDMS is a specific inhibitor of the ω-hydroxylase enzyme. There was a significant stimulation of transport. *P < 0.05 vs. control. Jv, volume absorption.