Extended Data Table 2. Ability of ntESCs to contribute to chimeras after injection into diploid (2N) or tetraploid (4N) host embryos.
Cell line | Host embryo type |
N | N recipients (pregnant) |
N Pups born /recipients |
N chimeras |
>90% chimerism |
Survived >90% chimerism |
---|---|---|---|---|---|---|---|
ntES2 | 2N | 217 | 12 (4) | 14/4 | 10 | 5 | 3 |
ntES2 | 4N | 165 | 14 (6) | 5/3 | 5 | 5 | 4 |
ntES3 | 2N | 250 | 13 (8) | 12/4 | 12 | 3 | 1 |
ntES8 | 2N | 90 | 6(3) | 9/3 | 9 | 8 | 7 |
ntES8 | 4N | 180 | 15(6) | 7/3 | 7 | 7 | 6 |
ntES9 | 2N | 137 | 9(5) | 5/3 | 5 | 5 | 4 |
Control ESCs | 4N | 313 | 22(11) | 19/6 | 19 | 19 | 4 |