Table 1. Patient Characteristics.
| Characteristic | N=41 |
|---|---|
| Median age, years (range) | 59 (21-80) |
| Male Sex (%) | 21 (51) |
| Diagnosis (%) | |
| AML | 37 (90.2) |
| MDS | 1 (2.4) |
| ALL | 1 (2.4) |
| Biphenotypic | 2 (5) |
| Median WBC (×109/l) | 8.3 (0.2 - 98.9) |
| Median BM Blasts , %, (range) | 63 (0* - 97) |
| Median No. of Prior Therapies (range) | 3 (1 - 7) |
| Cytogenetics (%) | |
| Diploid | 12 (29.3) |
| Poor Risk | 29 (70.7) |
N represents the total number of patients in the study. AML=Acute myeloid leukaemia; MDS=Myelodysplastic syndrome; ALL=Acute lymphoblastic leukaemia; Biphenotypic=Acute biphenotypic leukaemia. WBC=White blood cell count; BM=Bone Marrow; Poor Risk cytogenetics defined as monosomy 5, monosomy 7, 11q23 abnormality, or complex karyotype (3 or more abnormalities).
*
Included one patient with a rapidly proliferative relapsed MDS/Myeloproliferative neoplasm with 0% bone marrow blasts but 100% marrow infiltration by high-risk myeloid neoplasm.