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. Author manuscript; available in PMC: 2014 Aug 7.

Published in final edited form as: Bioorg Med Chem. 2013 Nov 6;22(1):623–632. doi: 10.1016/j.bmc.2013.10.040

(A) [¹⁸F]STI-571 PET images of Bcr-Abl expression in K562 tumors (right shoulder). PET images of [¹⁸F]FDG accumulation are provided for comparison. (B) [¹⁸F]STI-571 PET images showing the higher uptake of the radiotracer in c-KIT overexpressing U87WT tumors (right shoulder) than in wild-type U87 tumors (left shoulder), which do not express c-KIT.

(A) [¹⁸F]STI-571 PET images of Bcr-Abl expression in K562 tumors (right shoulder). PET images of [¹⁸F]FDG accumulation are provided for comparison. (B) [¹⁸F]STI-571 PET images showing the higher uptake of the radiotracer in c-KIT overexpressing U87WT tumors (right shoulder) than in wild-type U87 tumors (left shoulder), which do not express c-KIT.