Figure 5. Effects of mutations affecting DNA replication on the growth and chromosome segregation defects in the gyrB(Ts) ΔtopA strain.
(a) Representative superimposed images of DIC and fluorescence pictures of DAPI-stained cells grown at the indicated temperatures as described in Materials and Methods. Size bars are 5 µm. Additional images are shown in Figure S1 and S2. (b) Spot tests were performed at the indicated temperatures. The strains used are derivatives of RFM475 (gyrB(Ts) ΔtopA). They are: VU155 (RFM475 oriC), VU188 (RFM475 dnaT) and VU176 (RFM475 holC2::aph).